By Paolo Sassone-Corsi, Yves Christen
Recent years have obvious magnificent advances within the box of circadian biology. those have attracted the curiosity of researchers in lots of fields, together with endocrinology, neurosciences, melanoma, and behaviour. by way of integrating a circadian view in the fields of endocrinology and metabolism, researchers may be in a position to demonstrate many, yet-unsuspected facets of ways organisms take care of adjustments within the atmosphere and next keep watch over of homeostasis. This box is beginning new avenues in our knowing of metabolism and endocrinology. A panel of the main uncommon investigators within the box accumulated jointly to debate the current country and the way forward for the sphere. The editors belief that this quantity might be of use to these colleagues who can be picking out up the problem to solve how the circadian clock could be detailed for the long run improvement of particular pharmacological innovations towards a few pathologies.
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Extra resources for A Time for Metabolism and Hormones
We found that flies fed at the wrong time laid fewer eggs than those fed at the correct time. However, these differences were not noted in a Clk mutant, indicating that they reflected an interaction of the time of feeding with endogenous clocks (Xu et al. 2011). We surmise that desynchrony of brain and peripheral clocks, achieved by an RF paradigm, reduced reproductive success. Control of Metabolism by Central and Peripheral Clocks in Drosophila 39 Metabolic Signals Also Affect Clocks in the Brain While this chapter focuses on the circadian control of metabolism, we have also uncovered effects of metabolic signals of central clock function and rest:activity behavior.
Science 337:165–166 Creyghton MP, Cheng AW, Welstead GG, Kooistra T, Carey BW, Steine EJ, Hanna J, Lodato MA, Frampton GM, Sharp PA, Boyer LA, Young RA, Jaenisch R (2010) Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc Natl Acad Sci USA 107:21931–21936 Czarna A, Berndt A, Singh H, Grudziecki A, Ladurner A, Timinszky G, Kramer A, Wolf E (2013) Structures of Drosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function. Cell 153:1394–1405 Fuda N, Ardehali M, Lis J (2009) Defining mechanisms that regulate RNA polymerase II transcription in vivo.
Science 263:1603–1606 Sehgal A, Rothenfluh-Hilfiker A, Hunter-Ensor M, Chen Y, Myers MP, Young MW (1995) Rhythmic expression of timeless: a basis for promoting circadian cycles in period gene autoregulation. Science 270:808–810 Xu K, Zheng X, Sehgal A (2008) Regulation of feeding and metabolism by neuronal and peripheral clocks in Drosophila. Cell Metab 8:289–300 Xu K, DiAngelo JR, Hughes ME, Hogenesch JB, Sehgal A (2011) The circadian clock interacts with metabolic physiology to influence reproductive fitness.